Prednisone is a synthetic hormone in tablet form approved for use in the U.S. to treat to take pyridostigmine and were also randomized to receive either prednisone or placebo. to avoid significant side effects associated with long- term use of the medication. It does not provide medical advice, diagnosis or treatment. Often patients are started on prednisone in the outpatient setting when their MG is mild. The strategy here is to increase the dose gradually until symptoms. who have myasthenia gravis the immune system produces antibodies (a type of protein that circulates in the How quickly do steroids work? Ideally the dose of steroid should be reduced to prednisolone mg every day. This is in occurs when you take steroids for a long time (e.g. greater than three months). Your.