What if I take too much? Taking too many prednisolone tablets by accident is unlikely to harm you. If you're worried, talk to your doctor or pharmacist. Prednisone and other corticosteroid pills, creams and injections can cause side effects. Creams and ointments can help heal many skin conditions. If the dosage is reduced too quickly, your adrenal glands may not have time to recover . Question. Currently I am on 20mg of Methotrexate a week, 2 pills a day of mg celebrex and mg prednisone a day plus 2ultram twice a.