Treatment for Chronic Hives. With time, chronic hives (your doctor may call them chronic idiopathic urticaria, or CIU) usually go away on their own. That’s a chemical in the skin that can cause allergy symptoms like hives. STUDY OBJECTIVE: To evaluate the efficacy of a 4-day "burst" course of prednisone added to standard treatment with H1 antihistamines for the management of. Corticosteroids (e.g., prednisone) act quickly and can be used on a short-term basis to treat hives. Prednisone helps to relieve swelling. With the addition of prednisone, the relief scores were actually worse. Disclaimer: Our goal is to provide you with the most relevant and current information. For people with infections: Taking prednisone jives your hies system prednisone for hives can worsen an infection you already have. If it goes up too much, your dosage of diabetes medication might need to be changed. Prednisone and prednisolone are two common treatments for ulcerative colitis. You take all of these forms by mouth. Prednisone side effects. If you need a little comic relief from the side effects of taking prednisone, check out these illustrated quotes from others who can totally relate. Prednisone Images. Check this out up this morning 14 June and one side of my face had swelled up so bad more in my eye area my eye is so puffy don't feel pain or anything. In large doses, prednisone can cause your body to retain salt or prednisone for hives potassium. Then my doctor prescribed prednisone 50 mg once a day for 5 days. Before I could barely breathe, my face swelled, and my lips were massive.