Hypokalemia (Low Potassium) chemotherapy side effect, causes, symptom management and when to contact your healthcare provider during cancer treatment. View drug interactions between Potassium Chloride in Sodium Chloride and prednisone. These medicines may also interact with certain foods or diseases. Quick easy-to-read overview of Prednisone. fluid retention, which may lead to blood pressure elevation and increased potassium excretion.