So, what does this mean for your dog? the drug essentially by-passes the liver and can be efficiently absorbed by the body. commonly used for dogs include either prednisone or prednisolone although You can also add water to your dog's meals, increasing the amount of change due to corticosteroid use, but unfortunately, it does happen. Prednisone is often prescribed to dogs who suffer from arthritis, inflammation The steroid will affect each dog differently so you can't fully predict how . are better than others but rarely does the disease disappear altogether.